Oncology Platform

Bioanalytical Services
Phenotyping Services
Efficacy and Pathology PlatformMetabolism PlatformOncology Platform
Anti-Tumor Drug Efficacy Evaluation
Patient Derived Xenograft (PDX) Mouse Models and Efficacy ServicesHumanized Immune Checkpoint Mouse Models and Efficacy Services
Non-GLP Toxicity Assessment Services
Metabolic Disease Efficacy Evaluation
Gout/Hyperuricemia Models and Efficacy ServicesHyperlipidemia Models and Efficacy ServicesAtherosclerosis Models and Efficacy ServicesLiver Disease Models and Efficacy ServicesType II Diabetes Models and Efficacy ServiceObesity Models and Efficacy Services
Autoimmune Disease Efficacy Evaluation
Neurodegenerative Disease Efficacy Evaluation
In Vitro TestingIn Vivo Biochemical ExaminingBehavioral AnalysisIn Vivo Drug Efficacy Evaluation
Cell Therapy & Gene Therapy Efficacy Evaluation

GemPharmatech has successfully developed multiple PDX models, which cover cancers such as gastrointestinal, liver, pancreatic, lung, and hematologic, for a wide variety of uses, including efficacy evaluations, clinical studies as treatment control, and pathogenesis studies. While conducting efficacy evaluations of immunomodulators like hPD-1/hPD-L1 and hCTLA4 antibodies, the company utilized mouse models with humanized immune systems prepared from PBMCs and HSCs by PDX and CDX techniques. Mouse models with humanized immune checkpoints require no reconstruction of the immune system; therefore, using such models in the preclinical evaluation of the immunomodulators is both more economical and more convenient.


They are capable of monitoring tumor volume and weight and providing a basis for research in hematology, clinical biochemistry, immunohistochemistry, and others.

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