Health Monitoring Program
Health Status
Mice intended for export are housed in our barrier facilities. Access to the facilities are strictly limited to trained laboratory and animal care personnel by key card access. Personal protective equipment (PPE) is required for entry into the facility which includes disposable gowns, shoe covers, gloves, hair bonnet and masks. Animal care personnel are dedicated to the facility and/or room. Animals are housed and maintained in positive-pressure, individually ventilated cages/units (IVC/U) which are changed every 1-2 weeks. Mice are provided with corncob bedding and paper nest enrichment and receive irradiated feed. All caging, bedding and enrichment are autoclaved prior to use. Processed water (reverse osmosis, chlorinated) is supplied by an Edstrom automatic watering system. Animals leaving the barrier cannot return to the facility.
Facility Control and Maintenance
Mice intended for export are housed in our barrier facilities. Access to the facilities are strictly limited to trained laboratory and animal care personnel by key card access. Personal protective equipment (PPE) is required for entry into the facility which includes disposable gowns, shoe covers, gloves, hair bonnet and masks. Animal care personnel are dedicated to the facility and/or room. Animals are housed and maintained in positive-pressure, individually ventilated cages/units (IVC/U) which are changed every 1-2 weeks. Mice are provided with corncob bedding and paper nest enrichment and receive irradiated feed. All caging, bedding and enrichment are autoclaved prior to use. Processed water (reverse osmosis, chlorinated) is supplied by an Edstrom automatic watering system. Animals leaving the barrier cannot return to the facility.
Importing Animals
For imports, only specific pathogen free (SPF) animals are accepted and must be rederived and tested prior to release into the barrier. These animals are quarantined in isolators, and samples (including hair, feces or serology samples) of the received mice are submitted to GemPharmatech (GPT) microbial testing center. Animals can only be transported to the breeding animal rooms by cesarean section or embryo transfer once passing microbial tests.
| VIRUSES | Method |
| Sendai virus (SV) | ELISA |
| Mouse hepatitis virus (MHV) | ELISA |
| Ectromelia virus (Ect) | ELISA |
| Lymphocytic choriomeningitis (LCMV) | ELISA |
| Minute virus of mice (MVM) | ELISA |
| Reovirus 3 (Reo-3) | ELISA |
| Pneumonia virus of mice (PVM) | ELISA |
| Theiler's Mouse Encephalomyelitis Virus (TMEV) | ELISA |
| Hantavirus (HV) | ELISA |
| Mouse Parvovirus (MPV) | ELISA |
| Polyoma Virus (POLY) | ELISA |
| Mouse Adenovirus (K87) (MAD 2) | ELISA |
| Mouse Adenovirus (FL) (MAD 1) | ELISA |
| LDH elevating virus (LDV) | ELISA |
| K virus | ELISA |
| Epizootic Diarrhea of Infant Mice (EDIM) | ELISA |
| Murine Norovirus (MNV) | ELISA |
| Mouse Cytomegalovirus (MCMV) | ELISA |
| Mouse Kidney Parvovirus (MKPV) | PCR |
| BACTERIA & MYCOPLASMA | Method |
| Tyzzer's organism | ELISA |
| Corynebacterium kutscheri | Culture |
| Mycoplasma pulmonis | ELISA |
| Helicobacter | Culture |
| Pseudomonas aeruginosa | Culture |
| Staphylococcus aureus | Culture |
| Klebsiella pneumoniae | Culture |
| Pasteurella pneumotropica | Culture |
| Pathogenic dermal fungi | PCR |
| Bordetella bronchiseptica | Culture |
| Streptobacillus moniliformis | Culture |
| Yesinia enterocolitica | PCR |
| Yersinia pseudotuberculosis | PCR |
| Cilia-Associated Respiratory Bacillus (CARB) | ELISA |
| Helicobacter | PCR |
| β-hemolyticstreptococcus | Culture |
| Streptococcus pneumoniae | Culture |
| Escherichia coli O115 a,C,K (B) | Culture |
| Corynebacterium bovis | Culture |
| PARASITES & PROTOZOA | Method |
| Ectoparasites, e.g., fleas, mites, and lice | Micro |
| Encephalitozoon cunicul | ELISA |
| Ciliata | Micro |
| Flagellata | Micro |
| Helminth, e.g., pinworms | Micro |
| Mouse hepatitis virus (MHV) | ELISA |
| Pneumocystis spp. | PCR |
| OTHER | Method |
Additionally, GemPharmatech partners with several respected institutions and organizations to breed and house mice. For information on the health monitoring and testing practices of these facilities, please contact us.